Suspension of Market Authorisation of Raptiva
2009/03/05 - News from medical groupsFollowing the decision of EMEA and FDA, Raptiva will be withdrawn in the next weeks due to the risk of LEMP.
We are now discussing, within the French Psoriasis Group, on the best strategy to shift to another treatment.
It would be quite interesting to know about the practical strategies being taken in the different countries in light of this suspension.
To open the discussion, please find here below the decision taken at Saint Louis Hospital, Paris, France. To contribute to the discussion please contact weboffice@psoriasis-international.org
« We call in our patients and we explain them why this medicine is being withdrawn, reminding them that we are talking about an extremely rare secondary effect, although serious enough to recommend its withdrawal.
After which, we shall discuss two possibilities:
- To stop Raptiva and to make a therapeutic window. This can be rather tempting, especially for our patients that have been cleared for a long time now. However, stopping Raptiva can provoke a violent rebound extremely difficult to control, even with anti-TNF. It is thus capital, if we wish to practice a therapeutic window, to be completely prepared to start rather quickly a relay treatment, if in need.
- To start immediately a relay with another treatment is probably the wisest thing to do. This treatment could be: a) a biological treatment and for cleared patients we can take the relay with Enbrel or eventually Humira; b) a classical treatment in patients who present absolutely no contraindication, which is quite common.
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